Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189268 | 0.83 | HTR6 (0.33) | HTR6HTR2A | |
| SCHEMBL27874174 | 0.83 | HTR2A (0.33) | HTR6HTR2ASIGMAR1KDM1AKDM4E | |
| SCHEMBL7164209 | 0.79 | GAA (0.34) | HTR6HTR2ACHRNA7TP53CYP3A4 | |
| SCHEMBL8149561 | 0.78 | HTR6 (0.33) | HTR6HTR2ACHRNA7 | |
| SCHEMBL8157271 | 0.76 | HTR2A (0.34) | HTR6HTR2A | |
| SCHEMBL2806909 | 0.76 | BRD4 (0.31) | HTR6HTR2A | |
| SCHEMBL6427869 | 0.75 | CHRNA7 (0.31) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL4467823 | 0.74 | HTR6 (0.32) | HTR6HTR2ASIGMAR1KDM1ARCOR1 | |
| SCHEMBL17386884 | 0.73 | HTR2A (0.34) | HTR6HTR2A | |
| SCHEMBL6294599 | 0.70 | CHRM3 (0.32) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133658-A2 | Flame retardant non-dripping polycarbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1985-03-06 | — | — | EP | disclosed |