Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8149561 | 0.82 | HTR6 (0.33) | CHRNA7PRCPHTR6HTR2A | |
| SCHEMBL8157271 | 0.80 | HTR2A (0.34) | HTR6HTR2A | |
| SCHEMBL2806909 | 0.80 | BRD4 (0.31) | BRD4CCL2HTR6HTR2A | |
| SCHEMBL6427869 | 0.79 | CHRNA7 (0.31) | CHRNA7TSHR | |
| SCHEMBL11034547 | 0.79 | HTR6 (0.33) | CHRNA7TP53HTR6HTR2ACYP3A4 | |
| SCHEMBL17386884 | 0.77 | HTR2A (0.34) | HTR6HTR2A | |
| SCHEMBL28189268 | 0.73 | HTR6 (0.33) | HTR6HTR2A | |
| SCHEMBL7719552 | 0.73 | HTR2A (0.36) | SMN1; SMN2TP53TSHRPRCPBRD4 | |
| SCHEMBL6290100 | 0.73 | CHRM3 (0.32) | — | |
| SCHEMBL6294599 | 0.73 | CHRM3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341775-A2 | PROCESS FOR THE PREPARATION OF MORPHOLINONES | Ciba SC Holding AG (CH) | 2003-09-10 | — | — | EP | disclosed |
| EP-1263860-A1 | NEW 3-ARYLBENZOFURANONES WITH ELECTRON-WITHDRAWING SUBSTITUENTS AS STABILIZERS | Ciba SC Holding AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002048123-A2 | PROCESS FOR THE PREPARATION OF MORPHOLINONES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |
| WO-2001059000-A1 | NEW 3-ARYLBENZOFURANONES WITH ELECTRON-WITHDRAWING SUBSTITUENTS AS STABILIZERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-08-16 | — | — | WO | disclosed |