Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoprothiolane SCHEMBL8408577 | 0.86 | ADRA1A (0.60) | ADRA1APDE4DNPC1LMNARAB9A | |
| Isoprothiolane SCHEMBL71267 | 0.86 | ADRA1A (0.60) | ADRA1APDE4DNPC1LMNARAB9A | |
| Isoprothiolane SCHEMBL5613732 | 0.82 | ADRA1A (0.56) | ADRA1APDE4DNPC1LMNARAB9A | |
| SCHEMBL9521449 | 0.81 | ADRA1A (0.50) | ADRA1APDE4DNPC1LMNARAB9A | |
| SCHEMBL10989060 | 0.79 | ADRA1A (0.40) | ADRA1APDE4D | |
| SCHEMBL11676374 | 0.79 | ADRA1A (0.56) | ADRA1APDE4DLMNA | |
| SCHEMBL11678429 | 0.79 | ADRA1A (0.56) | ADRA1APDE4D | |
| SCHEMBL11616325 | 0.79 | ADRA1A (0.49) | ADRA1APDE4DNPC1LMNARAB9A | |
| SCHEMBL9521064 | 0.74 | ADRA1A (0.60) | ADRA1APDE4D | |
| SCHEMBL9521561 | 0.74 | ADRA1A (0.41) | ADRA1APDE4DNPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59042378-A | — | — | None | — | — | JP | disclosed |
| JP-S5942378-A | DITHIOLANE DERIVATIVE | NIPPON NOHYAKU CO LTD | 1984-03-08 | — | — | JP | disclosed |