Isoprothiolane

Isoprothiolane

SCHEMBL71267

CC(C)OC(=O)C(C(=O)OC(C)C)=C1SCCS1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.60
PDE4D Q08499 1/20 0.60
TSHR P16473 1/20 0.36
LMNA P02545 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.33
CA12 O43570 3/20 0.31
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
CA7 P43166 3/20 0.31
CA9 Q16790 3/20 0.31
CA14 Q9ULX7 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoprothiolane SCHEMBL8408577 1.00 ADRA1A (0.60) ADRA1APDE4DTSHRLMNANPC1
Isoprothiolane SCHEMBL5613732 0.96 ADRA1A (0.56) ADRA1APDE4DTSHRLMNANPC1
SCHEMBL11676374 0.92 ADRA1A (0.56) ADRA1APDE4DTSHRLMNASMN1; SMN2
SCHEMBL11678429 0.92 ADRA1A (0.56) ADRA1APDE4DTSHRSMN1; SMN2GAA
SCHEMBL9521449 0.90 ADRA1A (0.50) ADRA1APDE4DTSHRLMNANPC1
SCHEMBL11616325 0.88 ADRA1A (0.49) ADRA1APDE4DTSHRLMNANPC1
SCHEMBL9521064 0.88 ADRA1A (0.60) ADRA1APDE4DTSHRSMN1; SMN2GAA
SCHEMBL11034587 0.86 ADRA1A (0.46) ADRA1APDE4DLMNANPC1RAB9A
SCHEMBL11614781 0.82 ADRA1A (0.42) ADRA1APDE4DLMNANPC1RAB9A
SCHEMBL9521561 0.79 ADRA1A (0.41) ADRA1APDE4DLMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27580 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070814-A 11 Bactericide composition for mainly preventing and controlling crop diseases caused by pyrifos oryzae and anthrax 南京农业大学 2026-05-22 CN claimed
WO-2026105160-A1 NOVEL AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2026-05-21 WO claimed
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
CN-122030409-A Sterilization composition and application thereof 海利尔药业集团股份有限公司 2026-05-15 CN claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-20260068884-A1 COMPOSITION USED FOR KILLING FUNGI AND METHOD FOR APPLYING COMPOSITION JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) 2026-03-12 US claimed
US-20260060254-A1 HERBICIDAL COMPOSITIONS BAYER AG (DE) 2026-03-05 US claimed
EP-4114183-B1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2026-02-25 EP claimed
US-RE50724-E1 4-membered ring carboxamides used as nematicides SYNGENTA CROP PROTECTION AG (CH) 2026-01-06 US claimed
WO-2025244856-A1 METHODS AND COMPOSITIONS RELATING TO ELQ COMPOUNDS OREGON HEALTH & SCIENCE UNIVERSITY (US) 2025-11-27 WO claimed
EP-0134112-B1 PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS OR TREATMENT OF KETOSIS IN LIVESTOCK NIHON NOHYAKU CO., LTD. (JP) 1991-04-03 EP claimed
US-5001143-A Pharmaceutical composition for prophylactic and preventive of ketosis of livestocks NIHON NOHYAKU CO., LTD. (JP) 1991-03-19 US claimed
CN-1049771-A Composition pesticide ICI PLC (GB) 1991-03-13 CN claimed
EP-0415568-A2 Insecticidal compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-03-06 EP claimed
EP-0415569-A2 Agrochemical compositions ZENECA LIMITED (GB) 1991-03-06 EP claimed
US-4910217-A Adithia derivative of an unsaturated diester NIHON NOHYAKU CO., LTD. (JP) 1990-03-20 US claimed
CN-86101763-B Pesticide composition 日本农药株式会社 1988-10-19 CN claimed
US-4731385-A NITROMETHYLENE DERIVATIVE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-03-15 US claimed
EP-0238726-A2 1,3-Dithio-2-ylidene malonates for curing fat necrosis NIHON NOHYAKU CO., LTD. (JP) 1987-09-30 EP claimed
US-4080467-A LIVER DISORDERS NIHON NOHYAKU CO., LTD. (JA) 1978-03-21 US claimed