Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287903 | 0.98 | HRH1 (0.42) | KDM4EHRH1TDP1HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL11036483 | 0.97 | HRH1 (0.43) | KDM4EHRH1TDP1HTR2ADRD3 | |
| SCHEMBL11037054 | 0.91 | HRH1 (0.51) | KDM4EHRH1TDP1HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL11035291 | 0.90 | HRH1 (0.52) | KDM4EHRH1TDP1HTR2ADRD3 | |
| SCHEMBL11036104 | 0.88 | KDM4E (0.41) | KDM4ETDP1DRD3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11034941 | 0.88 | HRH1 (0.53) | KDM4EHRH1TDP1HTR2ADRD3 | |
| SCHEMBL11037599 | 0.86 | HTR7 (0.41) | DRD3KCNH2MEN1KMT2APOLB | |
| SCHEMBL11100917 | 0.86 | SCN9A (0.37) | HRH1TDP1HTR2ADRD3HTR2B | |
| Hydrochloric Acid SCHEMBL11037586 | 0.85 | HTR7 (0.41) | DRD3KCNH2MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL11034454 | 0.85 | HRH1 (0.38) | HRH1TDP1HTR2ADRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048705-B1 | 2-(4-(DIPHENYLMETHYLENE)-1-PIPERIDINYL)-ACETIC ACIDS AND THEIR AMIDES, THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | U C B, S.A. (BE) | 1984-07-11 | — | — | EP | disclosed |
| US-4443460-A | ANTIALLERGENS, ANTIHISTAMINES, ANTISPASMODICS, BRONCHODILATORS | UCB, SOCIETE ANONYME (BE) | 1984-04-17 | — | — | US | disclosed |
| EP-0048705-A1 | 2-(4-(Diphenylmethylene)-1-piperidinyl)-acetic acids and their amides, their preparation and pharmaceutical preparations containing them | U C B, S.A. (BE) | 1982-03-31 | — | — | EP | disclosed |