Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.36 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624249 | 0.78 | LMNA (0.57) | SMN1; SMN2HSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL11810613 | 0.77 | CYP3A4 (0.51) | SMN1; SMN2HSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL28826019 | 0.72 | HSD17B10 (0.53) | HSD17B10TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL2494214 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL2494211 | 0.72 | SMN1; SMN2 (0.55) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL16620271 | 0.72 | CA12 (0.47) | SMN1; SMN2HSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL10334267 | 0.71 | SMN1; SMN2 (0.60) | SMN1; SMN2HSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL6513061 | 0.71 | HSD17B10 (0.56) | HSD17B10TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL17818519 | 0.71 | HSD17B10 (0.56) | HSD17B10TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL25698390 | 0.71 | HSD17B10 (0.56) | HSD17B10TSHRALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59144749-A | — | — | None | — | — | JP | disclosed |
| JP-S59144749-A | SCHIFF BASE HAVING MEGATIVE DIELECTRIC ANISOTROPY | CHISSO CORP | 1984-08-18 | — | — | JP | disclosed |