Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369640 | 0.82 | LMNA (0.54) | LMNAALDH1A1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL6420527 | 0.82 | LMNA (0.54) | LMNAALDH1A1SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL6422393 | 0.81 | LMNA (0.58) | LMNAALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL22078673 | 0.80 | CYP3A4 (0.43) | LMNAHSD17B10ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL11034700 | 0.78 | SMN1; SMN2 (0.42) | LMNAHSD17B10TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1879318 | 0.77 | CYP3A4 (0.41) | LMNAHSD17B10ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL11746525 | 0.77 | CYP3A4 (0.46) | LMNAHSD17B10TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL11746515 | 0.77 | CYP3A4 (0.46) | LMNAHSD17B10TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7769756 | 0.76 | CYP3A4 (0.54) | LMNAHSD17B10ALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL1871731 | 0.76 | CYP3A4 (0.54) | LMNAHSD17B10ALDH1A1CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406770-A | Metallomesogen dyestuff | 哥兹有限公司 | 2017-11-28 | — | — | CN | disclosed |
| US-5843333-A | Metallo organo liquid crystals in a polymer matrix | SNIARICERCHE S.C.P.A (IT) | 1998-12-01 | — | — | US | disclosed |