Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.55 |
| ▸ | CCKBR | P32239 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160251 | 0.83 | OPRK1 (0.58) | OPRK1PDE4DCCKBRLMNAPDE3A | |
| SCHEMBL7895739 | 0.81 | OPRK1 (0.56) | OPRK1PDE4DCCKBRLMNAPDE3A | |
| SCHEMBL10811993 | 0.80 | OPRK1 (0.55) | OPRK1PDE4DCCKBRLMNAPDE3A | |
| SCHEMBL11116621 | 0.78 | OPRK1 (0.54) | OPRK1PDE4DCCKBRLMNAPDE3A | |
| SCHEMBL11084788 | 0.77 | OPRK1 (0.49) | OPRK1PDE4DCCKBRLMNAPDE3A | |
| SCHEMBL11713995 | 0.77 | OPRK1 (0.53) | OPRK1PDE4DCCKBRLMNAPDE3A | |
| SCHEMBL19006657 | 0.74 | CCKBR (0.51) | OPRK1PDE4DCCKBR | |
| SCHEMBL11117909 | 0.74 | CCKBR (0.49) | OPRK1PDE4DCCKBRLMNAPDE3A | |
| SCHEMBL19006733 | 0.74 | CCKBR (0.51) | OPRK1PDE4DCCKBR | |
| SCHEMBL11199713 | 0.71 | OPRK1 (0.49) | OPRK1PDE4DCCKBRLMNAPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476134-A | TRANQUILIZERS; NEUROLEPTIC AGENTS | THE UPJOHN COMPANY (US) | 1984-10-09 | — | — | US | disclosed |