Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.56 |
| ▸ | HTR2B | P41595 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 4/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533310 | 0.83 | ACHE (0.50) | ACHEHTR2BHTR2CHTR2ATSHR | |
| SCHEMBL11533307 | 0.83 | ACHE (0.50) | ACHEHTR2BHTR2CHTR2ATSHR | |
| SCHEMBL11533311 | 0.83 | ACHE (0.50) | ACHEHTR2BHTR2CHTR2ATSHR | |
| Hydrochloric Acid SCHEMBL9592368 | 0.81 | ACHE (0.63) | ACHEHTR2BHTR2CHTR2ATSHR | |
| SCHEMBL7939001 | 0.77 | ACHE (0.65) | ACHEHTR2BHTR2CHTR2ATSHR | |
| SCHEMBL14157895 | 0.76 | ACHE (0.63) | ACHETSHRMETAP1MAPT | |
| SCHEMBL8261218 | 0.76 | HTR2B (0.44) | HTR2BHTR2CHTR2ATSHRLMNA | |
| SCHEMBL8261219 | 0.76 | HTR2B (0.44) | HTR2BHTR2CHTR2ATSHRLMNA | |
| SCHEMBL14328460 | 0.74 | ACHE (0.57) | ACHEHTR2BHTR2CHTR2ATSHR | |
| SCHEMBL12998132 | 0.74 | ACHE (0.57) | ACHEHTR2BHTR2CHTR2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525360-A | Anti-psychotic phenylindene derivatives and acid addition salts thereof | KEFALAS A/S (DK) | 1985-06-25 | — | — | US | disclosed |
| EP-0110521-A2 | Phenylindene derivatives, acid addition salts thereof, and methods of preparation | KEFALAS A/S (DK) | 1984-06-13 | — | — | EP | disclosed |