Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | HTR2C | P28335 | 9/20 | 0.44 |
| ▸ | HTR2B | P41595 | 9/20 | 0.44 |
| ▸ | HTR2A | P28223 | 8/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533311 | 1.00 | ACHE (0.50) | ACHEHTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL11533310 | 1.00 | ACHE (0.50) | ACHEHTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL11034810 | 0.83 | ACHE (0.56) | ACHEHTR2CHTR2BHTR2AMETAP1 | |
| Hydrochloric Acid SCHEMBL9592368 | 0.79 | ACHE (0.63) | ACHEHTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL14328460 | 0.78 | ACHE (0.57) | ACHEHTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL12998132 | 0.78 | ACHE (0.57) | ACHEHTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL7376647 | 0.77 | HTR2C (0.42) | HTR2CHTR2BHTR2ASIGMAR1 | |
| SCHEMBL7939001 | 0.74 | ACHE (0.65) | ACHEHTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL13391138 | 0.74 | ACHE (0.56) | ACHEHTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL14157895 | 0.73 | ACHE (0.63) | ACHEMETAP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150136-A | ANTIDEPRESSANTS, ANALGESICS | SANDOZ LTD. (CH) | 1979-04-17 | — | — | US | disclosed |