Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29883158 | 0.84 | TDP1 (0.71) | TDP1L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL2944497 | 0.84 | TDP1 (0.71) | TDP1L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL2188598 | 0.84 | TDP1 (0.71) | TDP1L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL27886037 | 0.83 | TDP1 (0.73) | TDP1L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL19090370 | 0.83 | TDP1 (0.73) | TDP1L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL18286136 | 0.83 | TDP1 (0.73) | TDP1L3MBTL1RAB9ANPC1TSHR | |
| Hydrochloric Acid SCHEMBL1503943 | 0.83 | TDP1 (0.69) | TDP1L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL222437 | 0.83 | TDP1 (0.69) | TDP1L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL23933096 | 0.81 | TDP1 (1.00) | TDP1L3MBTL1RAB9ANPC1TSHR | |
| SCHEMBL2952697 | 0.80 | TSHR (0.69) | TDP1L3MBTL1RAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59042368-A | — | — | None | — | — | JP | disclosed |
| EP-3686196-A1 | POLYCYCLIC COMPOUND ACTING AS IDO INHIBITOR AND/OR IDO-HDAC DUAL INHIBITOR | Hangzhou Innogate Pharma Co., Ltd. (CN) | 2020-07-29 | — | — | EP | disclosed |
| JP-S5942368-A | SUBSTITUTED ACETYLAMINOPYRIDINE COMPOUND AND FUNGICIDAL AND MITICIDAL AGENT CONTAINING THE SAME | ISHIHARA SANGYO KAISHA LTD | 1984-03-08 | — | — | JP | disclosed |