Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035166 | 0.85 | PLA2G4B (0.57) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10881343 | 0.82 | ADRB1 (0.71) | ADRB1ADRB3ADRB2KMT2AMEN1 | |
| SCHEMBL28758860 | 0.77 | NPC1 (0.65) | ADRB1ADRB3ADRB2KMT2ANPC1 | |
| SCHEMBL5181351 | 0.76 | MAPT (0.64) | KMT2ANPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL7635847 | 0.75 | NPC1 (0.84) | KMT2ANPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL5182280 | 0.75 | KMT2A (0.59) | KMT2ANPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL10877974 | 0.74 | NPC1 (0.65) | ADRB1ADRB3ADRB2KMT2ANPC1 | |
| Iodide SCHEMBL30758616 | 0.74 | NPC1 (0.82) | KMT2ANPC1RAB9ASMN1; SMN2CHRNB2 | |
| Hydrochloric Acid SCHEMBL10880277 | 0.73 | NPC1 (0.63) | ADRB1ADRB3ADRB2KMT2ANPC1 | |
| SCHEMBL11252520 | 0.73 | PTGS1 (0.58) | ADRB1ADRB3ADRB2KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503075-A | ADRENERGIC BLOCKING AGENTS | A. MENARINI S.A.S. (IT) | 1985-03-05 | — | — | US | disclosed |
| EP-0100051-A1 | New derivatives of 1-alkylamine-(4(p-alkyloxy-benzamide)phenoxy)-2-propanol, having beta-sympatholytic activity, their salts, and production processes thereof | A. Menarini S.a.S. (IT) | 1984-02-08 | — | — | EP | disclosed |