Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181351 | 0.88 | MAPT (0.64) | KMT2ANPC1MEN1NR1H4CHRNB2 | |
| SCHEMBL5182626 | 0.88 | NR1H4 (0.67) | KMT2ANPC1MEN1NR1H4THRB | |
| SCHEMBL5182517 | 0.81 | NR1H4 (0.62) | KMT2ANPC1MEN1NR1H4THRB | |
| SCHEMBL5181024 | 0.78 | THRB (0.60) | KMT2ANPC1MEN1NR1H4THRB | |
| SCHEMBL27917022 | 0.78 | ALDH1A1 (0.66) | KMT2ANPC1MEN1POLBMAPT | |
| SCHEMBL27931850 | 0.78 | ALDH1A1 (0.66) | KMT2ANPC1MEN1POLBMAPT | |
| SCHEMBL27916978 | 0.78 | ALDH1A1 (0.66) | KMT2ANPC1MEN1POLBMAPT | |
| SCHEMBL5182983 | 0.78 | MEN1 (0.52) | KMT2ANPC1MEN1THRBMAPT | |
| SCHEMBL15413191 | 0.77 | NPC1 (0.78) | KMT2ANPC1MEN1MAPTKDM4E | |
| SCHEMBL5184066 | 0.77 | NPC1 (0.54) | KMT2ANPC1MEN1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1526149-B1 | Aromatic amide block copolymer and process of producing the same | TOSOH CORP (JP) | 2007-05-23 | — | — | EP | disclosed |
| US-7129314-B2 | Aromatic amide block copolymer and process of producing the same | TOSOH CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20050090639-A1 | Aromatic amide block copolymer and process of producing the same | TOSOH CORPORATION (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1526149-A1 | Aromatic amide block copolymer and process of producing the same | Tosoh Corporation (JP) | 2005-04-27 | — | — | EP | disclosed |