SCHEMBL11034971

SCHEMBL11034971

COC(Br)(Br)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.46
TSHR P16473 2/20 0.46
CES1 P23141 1/20 0.43
KCNN4 O15554 5/20 0.43
ALDH1A1 P00352 4/20 0.42
ALOX15 P16050 1/20 0.42
CA4 P22748 1/20 0.39
CYP1A2 P05177 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
CYP3A4 P08684 1/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1264373 0.80 MAPK1 (0.48) MAPK1TSHRCES1KCNN4ALDH1A1
SCHEMBL28797203 0.78 MAPK1 (0.46) MAPK1TSHRCES1KCNN4ALDH1A1
SCHEMBL18663547 0.77 MAPK1 (0.50) MAPK1TSHRKCNN4ALDH1A1ALOX15
SCHEMBL914885 0.76 ALDH1A1 (0.50) MAPK1TSHRCES1KCNN4ALDH1A1
SCHEMBL4073627 0.76 TSHR (0.50) MAPK1TSHRCES1KCNN4ALDH1A1
SCHEMBL10707751 0.76 TSHR (0.50) MAPK1TSHRCES1KCNN4ALDH1A1
SCHEMBL10499996 0.76 TSHR (0.50) MAPK1TSHRCES1KCNN4ALDH1A1
SCHEMBL28337912 0.75 TSHR (0.44) MAPK1TSHRCES1KCNN4ALDH1A1
Methoxytriphenylmethane SCHEMBL9103 0.74 MAPK1 (0.48) MAPK1TSHRCES1KCNN4ALDH1A1
SCHEMBL1659349 0.74 MAPK1 (0.48) MAPK1TSHRCES1KCNN4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59039846-A None JP disclosed
JP-S5939846-A PREPARATION OF ANISALDEHYDE NIPPON TOKUSHU NOYAKU SEIZO KK 1984-03-05 JP disclosed