Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3291029 | 0.79 | HTR6 (0.62) | HTR6ALDH1A1KDM4EGAAPKM | |
| SCHEMBL8852806 | 0.78 | HTR6 (0.56) | HTR6ALDH1A1KDM4EGAAPKM | |
| SCHEMBL11593088 | 0.75 | HTR6 (0.53) | HTR6ALDH1A1KDM4EGAAPKM | |
| SCHEMBL10777232 | 0.73 | CYP2D6 (0.49) | HTR6GAAPOLBGFERTSHR | |
| SCHEMBL11035205 | 0.73 | HTR6 (0.50) | HTR6ALDH1A1KDM4EGAAPKM | |
| SCHEMBL26294642 | 0.72 | HTR6 (0.53) | HTR6ALDH1A1KDM4EGAAPKM | |
| SCHEMBL15444 | 0.72 | HTR6 (0.74) | HTR6ALDH1A1KDM4EGAAPKM | |
| SCHEMBL1662788 | 0.70 | HTR6 (0.50) | HTR6ALDH1A1KDM4EGAAPKM | |
| SCHEMBL17774701 | 0.69 | HTR6 (0.69) | HTR6ALDH1A1KDM4EGAAPKM | |
| SCHEMBL30751995 | 0.69 | HTR6 (1.00) | HTR6ALDH1A1KDM4EGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165422-A1 | Substituted bis-(4-aminophenyl)-sulphones, their preparation and their use as medicines | Dr. Karl Thomae GmbH (DE) | 1985-12-27 | — | — | EP | disclosed |