SCHEMBL11035295

SCHEMBL11035295

C[Si](C)(C)CCSCCNCCSCC[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10941659 0.82 TSHR (0.36) TSHR
SCHEMBL10941794 0.81
SCHEMBL10596828 0.80 ADH1B (0.39) TSHR
SCHEMBL10596212 0.75 TSHR (0.75) TSHR
SCHEMBL10596419 0.73 MAPT (0.45) TSHR
Fumaric Acid SCHEMBL10941523 0.71 KDM4E (0.34) TSHR
SCHEMBL8691101 0.70 CYP1A2 (0.34) TSHR
SCHEMBL6665671 0.70 ALDH1A1 (0.30) TSHR
SCHEMBL10595566 0.69 ALDH1A1 (0.48) TSHR
SCHEMBL10941859 0.69 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59070693-A None JP disclosed
JP-S5970693-A NOVEL ORGANOSILICON COMPOUND, ITS NON-TOXIC SALT, ITS PREPARATION AND ANTITUMOR AGENT CONTAINING SAID COMPOUND AS ACTIVE COMPONENT SANWA KAGAKU KENKYUSHO:KK 1984-04-21 JP disclosed