SCHEMBL11035296

SCHEMBL11035296

CC(C)(NC(=O)Cc1ccccc1Cl)c1cccc(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNJ5 P48544 7/20 0.58
KCNJ3 P48549 7/20 0.58
KCNJ6 P48051 3/20 0.58
TRPV1 Q8NER1 3/20 0.50
ANO1 Q5XXA6 2/20 0.46
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
POLB P06746 1/20 0.44
THRB P10828 1/20 0.44
P2RX4 Q99571 2/20 0.43
TP53 P04637 2/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
ERCC1 P07992 1/20 0.43
ERCC4 Q92889 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11056164 0.90 KCNJ5 (0.58) KCNJ5KCNJ3KCNJ6TRPV1ANO1
SCHEMBL9364175 0.88 KCNJ5 (0.58) KCNJ5KCNJ3KCNJ6ANO1ALDH1A1
SCHEMBL11038352 0.87 TRPV1 (0.47) KCNJ5KCNJ3KCNJ6TRPV1ANO1
SCHEMBL11134551 0.85 KMT2A (0.52) KCNJ5KCNJ3KCNJ6TRPV1ANO1
SCHEMBL11036352 0.79 ALDH1A1 (0.48) KCNJ5KCNJ3KCNJ6ANO1ALDH1A1
SCHEMBL11402011 0.78 MEN1 (0.53) ANO1ALDH1A1MEN1KMT2A
SCHEMBL10989847 0.78 ANO1 (0.57) KCNJ5KCNJ3KCNJ6ANO1ALDH1A1
SCHEMBL3677265 0.78 USP36 (0.49) ALDH1A1LMNAPOLBNPC1RAB9A
SCHEMBL20738625 0.75 USP36 (0.49) ALDH1A1LMNAPOLB
SCHEMBL11033536 0.75 KCNJ5 (0.50) KCNJ5KCNJ3KCNJ6TRPV1ANO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4484942-A N-Benzylphenylacetamide derivatives, and their production and use as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-27 US claimed
EP-0033611-B1 N-BENZYLPHENYLACETAMIDE DERIVATIVES, THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-03-14 EP claimed
EP-0033611-A2 N-Benzylphenylacetamide derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-12 EP claimed