Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ5 | P48544 | 5/20 | 0.58 |
| ▸ | KCNJ3 | P48549 | 5/20 | 0.58 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134551 | 0.91 | KMT2A (0.52) | KCNJ5KCNJ3KCNJ6NPC1RAB9A | |
| SCHEMBL11035296 | 0.88 | KCNJ5 (0.58) | KCNJ5KCNJ3KCNJ6NPC1RAB9A | |
| SCHEMBL11056164 | 0.88 | KCNJ5 (0.58) | KCNJ5KCNJ3KCNJ6NPC1RAB9A | |
| SCHEMBL10989847 | 0.84 | ANO1 (0.57) | KCNJ5KCNJ3KCNJ6NPC1RAB9A | |
| SCHEMBL118815 | 0.82 | NPC1 (0.64) | KCNJ5KCNJ3KCNJ6NPC1RAB9A | |
| SCHEMBL29414021 | 0.82 | NPC1 (0.64) | KCNJ5KCNJ3KCNJ6NPC1RAB9A | |
| SCHEMBL11036352 | 0.80 | ALDH1A1 (0.48) | KCNJ5KCNJ3KCNJ6NPC1RAB9A | |
| SCHEMBL11220297 | 0.79 | MEN1 (0.57) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL9360320 | 0.79 | P2RX7 (0.55) | P2RX7ALDH1A1KMT2APOLBCYP3A4 | |
| SCHEMBL28351223 | 0.77 | CNR1 (0.54) | KCNJ5KCNJ3KCNJ6P2RX7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6116218-A | — | — | None | — | — | JP | disclosed |
| JP-H06116218-A | N-@(3754/24)ALPHA,ALPHA-DIMETHYLBENZYL)PHENYLACETAMIDE DERIVATIVE | MITSUBISHI PETROCHEM CO LTD | 1994-04-26 | — | — | JP | disclosed |