Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 1.00 |
| ▸ | CASP2 | P42575 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.61 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25430532 | 0.86 | CASP3 (0.76) | CASP3CASP2HTTALDH1A1KMT2A | |
| SCHEMBL30516491 | 0.84 | CASP3 (0.72) | CASP3CASP2HTTALDH1A1KMT2A | |
| SCHEMBL24335866 | 0.84 | CASP3 (0.72) | CASP3CASP2HTTALDH1A1KMT2A | |
| SCHEMBL24335146 | 0.84 | CASP3 (0.72) | CASP3CASP2HTTALDH1A1KMT2A | |
| SCHEMBL24335274 | 0.84 | CASP3 (0.72) | CASP3CASP2HTTALDH1A1KMT2A | |
| SCHEMBL2920986 | 0.83 | CASP3 (0.70) | CASP3CASP2HTTALDH1A1KMT2A | |
| SCHEMBL30516492 | 0.82 | CASP3 (0.70) | CASP3CASP2HTTALDH1A1KMT2A | |
| SCHEMBL29064837 | 0.82 | CASP3 (0.70) | CASP3CASP2HTTALDH1A1KMT2A | |
| SCHEMBL24335540 | 0.81 | CASP3 (0.68) | CASP3CASP2HTTALDH1A1KMT2A | |
| SCHEMBL24335266 | 0.81 | CASP3 (0.68) | CASP3CASP2HTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59141592-A | — | — | None | — | — | JP | disclosed |
| JP-S59141592-A | 1,2,3,4-TETRAHYDRO-2-QUINOXALONE DERIVATIVE, ITS PREPARATION AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | SUMITOMO CHEM CO LTD | 1984-08-14 | — | — | JP | disclosed |