SCHEMBL11035452

SCHEMBL11035452

CCCC(O)C(CC)CC(N)CC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
SPHK1 Q9NYA1 2/20 0.33
METAP1 P53582 1/20 0.33
CYP2D6 P10635 2/20 0.31
GMNN O75496 1/20 0.31
POLB P06746 1/20 0.31
THPO P40225 1/20 0.31
MTOR P42345 1/20 0.31
BLM P54132 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CETP P11597 1/20 0.31
HTT P42858 1/20 0.31
UBE2N P61088 1/20 0.31
GRIK1 P39086 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5556231 0.78 LMNA (0.75) LMNASPHK1METAP1CYP2D6GMNN
SCHEMBL6334658 0.77 LMNA (0.60) LMNA
SCHEMBL20298310 0.76 LMNA (0.71) LMNASPHK1METAP1CYP3A4
SCHEMBL10896611 0.75 LMNA (0.62) LMNASPHK1METAP1CYP2D6GMNN
SCHEMBL3679182 0.74 LMNA (0.56) LMNA
SCHEMBL23072529 0.73 METAP1 (0.35) METAP1
SCHEMBL602930 0.72 LMNA (0.65) LMNASPHK1CYP2D6GMNNPOLB
Ethohexadiol SCHEMBL38007 0.72 LMNA (1.00) LMNASPHK1CYP2D6GMNNPOLB
Ethohexadiol SCHEMBL6282991 0.72 LMNA (1.00) LMNASPHK1CYP2D6GMNNPOLB
SCHEMBL5954802 0.71 LMNA (0.52) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034968-B1 N-SUBSTITUTED SUCCINIMIDES, THEIR PREPARATION AND THEIR USE AS ADDITIVES FOR FUELS Institut Français du Pétrole (FR) 1984-02-15 EP claimed
US-4422856-A ANTIRUST AGENTS, DETERGENT INSTITUT FRANCAIS DU PETROLE (FR) 1983-12-27 US claimed