Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13470664 | 0.83 | CYP1A2 (0.41) | TAAR1HTR2ANPC1NFKB1MAPK1 | |
| SCHEMBL22930106 | 0.83 | LMNA (0.47) | TAAR1HTR2ANPC1NFKB1MAPK1 | |
| SCHEMBL14116837 | 0.81 | TAAR1 (0.41) | TAAR1HTR2ASIGMAR1NPC1NFKB1 | |
| SCHEMBL25708224 | 0.80 | TAAR1 (0.44) | TAAR1L3MBTL1LMNAKMT2AALDH1A1 | |
| SCHEMBL983854 | 0.80 | ESR1 (0.57) | TAAR1SIGMAR1L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL8960092 | 0.79 | SIGMAR1 (0.47) | TAAR1HTR2ASIGMAR1NPC1NFKB1 | |
| SCHEMBL11374644 | 0.78 | SIGMAR1 (0.44) | TAAR1HTR2ASIGMAR1NPC1NFKB1 | |
| SCHEMBL1498212 | 0.77 | CYP1A2 (0.42) | SIGMAR1NPC1NFKB1MAPK1RAB9A | |
| SCHEMBL27881438 | 0.76 | SMN1; SMN2 (0.59) | TAAR1HTR2ANPC1NFKB1MAPK1 | |
| SCHEMBL687846 | 0.76 | SMN1; SMN2 (0.59) | TAAR1HTR2ANPC1NFKB1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59059635-A | — | — | None | — | — | JP | disclosed |
| JP-S5959635-A | 4,4'-SUBSTITUTED BIPHENYL DERIVATIVE | SEIKO EPSON CORP | 1984-04-05 | — | — | JP | disclosed |