Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11688010 | 0.88 | TSHR (0.36) | TSHRTHRBSLC22A1DNM1ALDH1A1 | |
| SCHEMBL17559522 | 0.78 | GAA (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10339083 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL10339085 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL10339084 | 0.77 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL31265382 | 0.75 | TSHR (0.38) | TSHRTHRBDNM1ALDH1A1 | |
| SCHEMBL18632074 | 0.72 | — | — | |
| SCHEMBL9517844 | 0.72 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL8743146 | 0.70 | TSHR (0.44) | TSHRTHRBSLC22A1DNM1ALDH1A1 | |
| SCHEMBL381358 | 0.70 | TSHR (0.44) | TSHRTHRBSLC22A1DNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0137718-A2 | Fungicidal triazoleethanols | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-17 | — | — | EP | disclosed |