SCHEMBL381358

SCHEMBL381358

CCCCCCC12OC1O2

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.44
ALDH1A1 P00352 3/20 0.37
DNM1 Q05193 7/20 0.36
LMNA P02545 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC22A1 O15245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8671830 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8743277 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL18632072 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL8743092 1.00 TSHR (0.44) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11580672 0.83 TSHR (0.61) TSHRALDH1A1
SCHEMBL23854647 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA
Hexadecane SCHEMBL23499901 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL11854960 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA
Decane SCHEMBL23499900 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA
Decane SCHEMBL170135 0.67 TSHR (1.00) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1447 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260048005-A1 INJECTABLE THERMOSENSITIVE HYDROGELS FOR A SUSTAINED RELEASE OF IRON NANOCHELATORS MASSACHUSETTS GEN HOSPITAL (US) 2026-02-19 US claimed
US-20260035519-A1 PROCESS FOR EFFICIENT CROSS-LINKING OF HYALURONIC ACID Galderma Holding SA (CH) 2026-02-05 US claimed
US-12454602-B2 Process for efficient cross-linking of hyaluronic acid Galderma Holding SA (CH) 2025-10-28 US claimed
EP-4590352-A1 MULTI-COMPONENT HYDROGEL GEL AND USES OF THE SAME Galderma Holding SA (CH) 2025-07-30 EP claimed
EP-4572752-A1 INJECTABLE THERMOSENSITIVE HYDROGELS FOR A SUSTAINED RELEASE OF IRON NANOCHELATORS The General Hospital Corporation (US) 2025-06-25 EP claimed
EP-4530308-A1 MULTI-CROSSLINKED GEL SYSTEM AND PRODUCT THEREOF, PREPARATION METHOD, AND USE Shanghai Qisheng Biological Preparation Co., Ltd. (CN) 2025-04-02 EP claimed
EP-4525942-A1 SYSTEMS AND METHODS FOR IMPROVED STERILE PROCESSING OF BIOLOGICAL MATERIAL Rosivo LLC (US) 2025-03-26 EP claimed
WO-2025029775-A1 SYSTEMS AND METHODS FOR IMPROVED STERILE PROCESSING OF BIOLOGICAL MATERIAL ROSIVO LLC (US) 2025-02-06 WO claimed
EP-4456936-A1 SOFT TISSUE AUGMENTATION USING INJECTABLE, NEUTRAL PH SOLUBLE COLLAGEN-GLYCOSAMINOGLYCAN COMPOSITIONS Shanghai Qisheng Biological Preparation Co., Ltd. (CN) 2024-11-06 EP claimed
WO-2024212266-A1 MULTI-CROSSLINKED GEL SYSTEM AND PRODUCT THEREOF, PREPARATION METHOD, AND USE 上海其胜生物制剂有限公司 2024-10-17 WO claimed
WO-2004106555-A2 HIGH-THROUGHPUT METHODS OF SCREENING DNA FOR DELETIONS AND OTHER MUTATIONS DOW AGROSCIENCES LLC (US) 2004-12-09 WO claimed
US-6762019-B2 Use in activated slides for making microarrays of nucleic acids; monomers with pendant epoxy groups to immobilize biological targets, diluent monomers or polymers, and monomers having a photoreactive group to surface treat the substrate SURMODICS, INC. 2004-07-13 US claimed
US-20040053236-A1 Reverse genetic strategy for identifying functional mutations in genes of known sequences NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-03-18 US claimed
EP-1139911-A4 METHOD FOR TISSUE FIXATION AV HEALING LLC (US) 2003-07-23 EP claimed
WO-2001075167-A1 REVERSE GENETIC STRATEGY FOR IDENTIFYING FUNCTIONAL MUTATIONS IN GENES OF KNOWN SEQUENCE FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2001-10-11 WO claimed
EP-1139911-A1 METHOD FOR TISSUE FIXATION USING EPOXIDES AV Healing LLC (US) 2001-10-10 EP claimed
WO-2000035374-A1 METHOD FOR TISSUE FIXATION AV HEALING LLC (US) 2000-06-22 WO claimed
US-5670052-A CROSSLINKED MEMBRANE EXXON RESEARCH & ENGINEERING COMPANY (US) 1997-09-23 US claimed
US-5550199-A MEMBRANES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-08-27 US claimed
EP-0097005-B1 THIOETHER-MODIFIED SEALANT COMPOSITIONS AND INSULATED GLASS ARTICLES SEALED THEREWITH MORTON THIOKOL, INC. (US) 1986-10-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260048005-A1 INJECTABLE THERMOSENSITIVE HYDROGELS FOR A SUSTAINED RELEASE OF IRON NANOCHELATORS CD44, FECH, HSF1 TSHR 563/4885THRB 2197/4885ALDH1A1 300/4885
US-20260035519-A1 PROCESS FOR EFFICIENT CROSS-LINKING OF HYALURONIC ACID CD44, TRHDE, HAO2 TSHR 1401/4885THRB 1377/4885ALDH1A1 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.