SCHEMBL11035620

SCHEMBL11035620

C=CC(C(=O)C(C)(C)C)n1ccnc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CHRM1 P11229 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
ADRA1A P35348 1/20 0.47
SLC6A3 Q01959 1/20 0.47
CYP24A1 Q07973 1/20 0.45
CYP17A1 P05093 3/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP26A1 O43174 9/20 0.36
CYP19A1 P11511 1/20 0.34
TBXAS1 P24557 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11039226 0.82 KMT2A (0.46) KMT2AMEN1CYP3A4ADORA3CHRM1
SCHEMBL11039225 0.82 KMT2A (0.46) KMT2AMEN1CYP3A4ADORA3CHRM1
SCHEMBL6898202 0.79 CYP17A1 (0.44) KMT2ACYP17A1KDM4ECYP26A1CYP19A1
SCHEMBL27749679 0.77 CYP17A1 (0.40) KMT2AMEN1CYP3A4ADORA3CHRM1
Hydrochloric Acid SCHEMBL28870357 0.77 CYP17A1 (0.43) CYP17A1KDM4ECYP26A1CYP19A1TBXAS1
Bromide SCHEMBL28405764 0.77 CYP17A1 (0.43) KMT2ACYP17A1KDM4ECYP26A1CYP19A1
SCHEMBL10576923 0.77 KMT2A (0.50) KMT2AMEN1CYP3A4ADORA3CHRM1
SCHEMBL28131809 0.77 ALDH1A1 (0.45) KMT2AMEN1CYP3A4ADORA3CHRM1
SCHEMBL11145880 0.76 KMT2A (0.52) KMT2AMEN1CYP3A4ADORA3CHRM1
SCHEMBL11151826 0.76 KMT2A (0.49) KMT2AMEN1CYP3A4ADORA3CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0041615-B1 USE OF IMIDAZOLYL-VINYL KETONES AND ALCOHOLS AS ANTIMICROBIAL AGENTS BAYER AG (DE) 1984-02-22 EP claimed
EP-0041615-A1 Use of imidazolyl-vinyl ketones and alcohols as antimicrobial agents BAYER AG (DE) 1981-12-16 EP claimed