SCHEMBL6898202

SCHEMBL6898202

C=CC(C(=O)O)n1ccnc1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.44
KDM4E B2RXH2 1/20 0.40
CYP26A1 O43174 10/20 0.39
CYP19A1 P11511 1/20 0.39
ALDH1A1 P00352 1/20 0.37
TBXAS1 P24557 2/20 0.36
EGLN3 Q9H6Z9 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28870357 0.98 CYP17A1 (0.43) CYP17A1KDM4ECYP26A1CYP19A1ALDH1A1
Bromide SCHEMBL28405764 0.98 CYP17A1 (0.43) CYP17A1KDM4ECYP26A1CYP19A1ALDH1A1
SCHEMBL29215164 0.90 KDM4E (0.41) CYP17A1KDM4ECYP26A1KMT2A
SCHEMBL27749679 0.83 CYP17A1 (0.40) CYP17A1KDM4ECYP26A1CYP19A1ALDH1A1
SCHEMBL27532228 0.82 CYP19A1 (0.40) CYP17A1KDM4ECYP26A1CYP19A1ALDH1A1
SCHEMBL11035620 0.79 KMT2A (0.47) CYP17A1KDM4ECYP26A1CYP19A1TBXAS1
SCHEMBL4551670 0.79 CYP17A1 (0.37) CYP17A1KDM4ECYP26A1CYP19A1ALDH1A1
SCHEMBL28131809 0.79 ALDH1A1 (0.45) CYP17A1KDM4ECYP26A1CYP19A1ALDH1A1
SCHEMBL4569650 0.79 CYP17A1 (0.50) CYP17A1KDM4ECYP26A1CYP19A1ALDH1A1
SCHEMBL9706448 0.78 KDM4E (0.55) CYP17A1KDM4ECYP26A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114725336-B Protective layer modified zinc anode material and preparation method and application thereof 武汉理工大学 2025-01-14 CN claimed
CN-114405545-B Cellulose inscription mimic enzyme, construction method and application thereof 河南科技大学 2024-06-07 CN claimed
CN-116396582-A Fluorescent polyion liquid gel and preparation method and application thereof 浙江理工大学嵊州创新研究院有限公司 2023-07-07 CN claimed
CN-116332854-A Preparation method of benzylidene hydantoin 浙江昂利泰制药有限公司 2023-06-27 CN claimed
CN-115353836-B Sulfur-containing octanoic acid anion terpolymer adhesive and preparation method thereof 浙江理工大学 2023-05-23 CN claimed
CN-113583180-B Polyionic liquid containing thioctic acid anions and preparation method thereof 浙江理工大学龙港研究院有限公司 2023-01-10 CN claimed
CN-115353836-A Thioctic acid anion-containing terpolymer adhesive and preparation method thereof 浙江理工大学 2022-11-18 CN claimed
CN-114725336-A Protective layer modified zinc anode material and preparation method and application thereof 武汉理工大学 2022-07-08 CN claimed
CN-114405545-A Cellulose endoblotting mimic enzyme, construction method and application thereof 河南科技大学 2022-04-29 CN claimed
CN-113583180-A Polyionic liquid containing thioctic acid anions and preparation method thereof 浙江理工大学龙港研究院有限公司 2021-11-02 CN claimed
CN-103265492-B Chlorinated 1-vinyl-3-carboxymethyl imidazole polymerizable acidic ionic liquid and synthetic method thereof UNIV NORTHWESTERN POLYTECHNIC 2015-04-01 CN claimed
CN-103265492-A Chlorinated 1-vinyl-3-carboxymethyl imidazole polymerizable acidic ionic liquid and synthetic method thereof UNIV NORTHWESTERN POLYTECHNIC 2013-08-28 CN claimed
CN-114725336-B Protective layer modified zinc anode material and preparation method and application thereof 武汉理工大学 2025-01-14 CN disclosed
CN-119143920-A Novel high-mechanical-strength high-toughness conductive polymer, preparation method thereof and application thereof as carbon-based composite bipolar plate binder 辽宁大学 2024-12-17 CN disclosed
CN-114405545-B Cellulose inscription mimic enzyme, construction method and application thereof 河南科技大学 2024-06-07 CN disclosed
CN-117777357-A Polyion liquid-based ion conductive elastomer based on synergistic effect of multiple supermolecule acting forces and preparation method and application thereof 辽宁大学 2024-03-29 CN disclosed
US-20030232790-A1 Dihydro-2h-napthalene-1-one inhibitors of ras farnesyl transferase WARNER-LAMBERT COMPANY 2003-12-18 US disclosed
EP-1276724-A2 DIHYDRO-2H-NAPHTHALENE-1-ONE INHIBITORS OF RAS FARNESYL TRANSFERASE WARNER-LAMBERT COMPANY (US) 2003-01-22 EP disclosed
WO-2001079179-A2 DIHYDRO-2H-NAPHTHALENE-1-ONE INHIBITORS OF RAS FARNESYL TRANSFERASE WARNER-LAMBERT COMPANY (US) 2001-10-25 WO disclosed
US-4243671-A ADMINISTERING 1-(3-PHENYL-2-PROPENYL)-1H-IMIDAZOLE E. R. SQUIBB & SONS, INC. (US) 1981-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232790-A1 Dihydro-2h-napthalene-1-one inhibitors of ras farnesyl transferase NRAS, FNTA, CYP46A1 CYP17A1 52/4885KDM4E 3826/4885CYP26A1 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.