Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FABP7 | O15540 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702685 | 0.84 | NPC1 (0.44) | NPC1RAB9AMEN1KMT2AMMP9 | |
| SCHEMBL6577884 | 0.80 | MMP9 (0.49) | NPC1RAB9AMEN1KMT2AMMP9 | |
| SCHEMBL6577382 | 0.77 | MMP9 (0.49) | NPC1RAB9AMEN1KMT2AMMP9 | |
| SCHEMBL45477 | 0.77 | CYP1A2 (0.42) | SMN1; SMN2MAPTTDP1 | |
| SCHEMBL6707429 | 0.76 | ATM (0.44) | NPC1RAB9AMEN1KMT2AMMP9 | |
| SCHEMBL828975 | 0.75 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AMMP9 | |
| SCHEMBL828968 | 0.75 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AMMP9 | |
| SCHEMBL31203529 | 0.75 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AMMP9 | |
| SCHEMBL109766 | 0.74 | MEN1 (0.52) | NPC1RAB9AMEN1KMT2AMMP9 | |
| SCHEMBL29377552 | 0.74 | MEN1 (0.52) | NPC1RAB9AMEN1KMT2AMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455331-A | Coating composition containing a rheology control additive of silica and polyvinyl pyrrolidone | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-19 | — | — | US | disclosed |
| US-4429066-A | AUTOMOBILES AND TRUCKS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4416941-A | AUTOMOTIVE PAINTS | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4411951-A | ACRYLIC ESTER RESIN CROSS LINKED WITH MELAMINE-FORMALDEHYDE RESIN BONDER | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-10-25 | — | — | US | disclosed |
| US-4404248-A | AUTOMOBILES; TRUCKS; AIRCRAFT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-09-13 | — | — | US | disclosed |
| US-4396680-A | Substrate coated with crater resistant acrylic enamel | E. I. DU PONT DE NEMOURS AND CO. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4371657-A | AMINO RESIN CROSSLINKING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-01 | — | — | US | disclosed |
| US-4330458-A | High solids coating composition of a blend of a low molecular weight acrylic polymer and a medium molecular weight acrylic polymer and an alkylated melamine cross-linking agent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| US-4276212-A | ACRYLIC ESTER COPOLYMER INCLUDING A HYDROXYALKYL ACRYLATE AND CHAIN TRANSFER AGENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-30 | — | — | US | disclosed |
| EP-0029598-A1 | An improved high solids coating composition of a low molecular weight acrylic polymer and a polyisocyanate cross-linking agent, and a substrate coated therewith | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| EP-0029596-A1 | An improved high solids coating composition of a low molecular weight acrylic polymer and a nitrogen resin cross-linking agent, and a substrate coated therewith | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |