SCHEMBL45477

SCHEMBL45477

O=C(O)c1ccc2c(c1C(=O)O)CC2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
METAP2 P50579 3/20 0.40
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 2/20 0.38
GSR P00390 1/20 0.37
ALOX15 P16050 2/20 0.37
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SELL P14151 1/20 0.35
SELP P16109 1/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
TSHR P16473 2/20 0.34
CA7 P43166 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5516985 0.92 CYP1A2 (0.37) CYP1A2METAP2ALDH1A1KDM4EGSR
SCHEMBL819226 0.88 METAP2 (0.51) CYP1A2METAP2ALDH1A1KDM4EHPGD
SCHEMBL819555 0.88 METAP2 (0.48) CYP1A2METAP2ALDH1A1KDM4EHPGD
SCHEMBL196225 0.85 CYP1A2 (0.41) CYP1A2METAP2ALDH1A1KDM4EGSR
SCHEMBL967549 0.83 CYP1A2 (0.44) CYP1A2METAP2ALDH1A1KDM4EGSR
Cyclohexane SCHEMBL5999616 0.82 CYP1A2 (0.38) CYP1A2METAP2ALDH1A1KDM4EGSR
Terephthalic Acid SCHEMBL3735419 0.79 TSHR (0.43) ALDH1A1KDM4EALOX15SMN1; SMN2TDP1
SCHEMBL7355316 0.77 PNMT (0.41) METAP2TSHR
SCHEMBL11035640 0.77 NPC1 (0.40) SMN1; SMN2MAPTTDP1
SCHEMBL22160715 0.76 CYP1A2 (0.37) CYP1A2METAP2ALDH1A1ALOX15SELL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3658470-B1 A DUAL-CHAMBER PACKAGE SYSTEM FOR ABSORBENT ARTICLES UNIV TSINGHUA (CN) 2023-12-13 EP claimed
US-10710765-B2 Base for hot-fill plastic containers GRAHAM PACKAGING COMPANY, L.P. (US) 2020-07-14 US claimed
EP-3658470-A1 A DUAL-CHAMBER PACKAGE SYSTEM FOR ABSORBENT ARTICLES Tsinghua University (CN) 2020-06-03 EP claimed
US-10236794-B2 Hybrid power generating device Research & Business Foundation Sungkyunkwan University (KR) 2019-03-19 US claimed
WO-2019019036-A1 A DUAL-CHAMBER PACKAGE SYSTEM FOR ABSORBENT ARTICLES TSINGHUA UNIVERSITY (CN) 2019-01-31 WO claimed
EP-2651651-B1 TRANSFER ARTICLE HAVING MULTI-SIZED PARTICLES AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2019-01-23 EP claimed
EP-3024741-B1 BASE FOR HOT-FILL PLASTIC CONTAINERS GRAHAM PACKAGING CO (US) 2018-05-16 EP claimed
EP-3024742-B1 BASE FOR HOT-FILL PLASTIC CONTAINERS GRAHAM PACKAGING CO (US) 2018-03-28 EP claimed
EP-3024741-A1 BASE FOR HOT-FILL PLASTIC CONTAINERS Graham Packaging Company, L.P. (US) 2016-06-01 EP claimed
EP-3024742-A1 BASE FOR HOT-FILL PLASTIC CONTAINERS Graham Packaging Company, L.P. (US) 2016-06-01 EP claimed
US-20060121262-A1 Process for the preparation of a composite polymeric material STMicroelectronics S.r. I (IT) 2006-06-08 US claimed
US-6878483-B2 Solid electrolyte lies between an anode foil and a cathode foil, a separator which is made of a nonwoven fabric containing polyester resin or its derivative NIPPON KODOSHI CORPORATION (JP) 2005-04-12 US claimed
WO-2003106107-A1 BRAKE RESURFACER AND METHODS OF RESURFACING A BRAKE ROTOR AND DRUM BRAKE TRU, INC. (US) 2003-12-24 WO claimed
US-20020117394-A1 Solid electrolyte lies between an anode foil and a cathode foil, a separator which is made of a nonwoven fabric containing polyester resin or its derivative NIPPON KODOSHI CORPORATION (JP) 2002-08-29 US claimed
US-6441299-B2 Covering member for solar battery BRIDGESTONE CORPORATION (JP) 2002-08-27 US claimed
EP-0323560-B1 Radiation-curable coating for thermoplastic substrates GEN ELECTRIC (US) 1994-10-26 EP claimed
US-4902578-A Radiation-curable coating for thermoplastic substrates GENERAL ELECTRIC COMPANY (US) 1990-02-20 US claimed
EP-0323560-A2 Radiation-curable coating for thermoplastic substrates GENERAL ELECTRIC COMPANY (US) 1989-07-12 EP claimed
US-4678114-A Method of wire bonding with applied insulative coating KABUSHIKI KAISHA TOSHIBA (JP) 1987-07-07 US claimed
US-4488674-A Bonding wire, semiconductor device having the same, and bonding method using the same TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1984-12-18 US claimed