SCHEMBL11035664

SCHEMBL11035664

O=C(c1occ2cccc(O)c12)c1occ2cccc(O)c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KMT2A Q03164 2/20 0.41
DNMT1 P26358 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
MCL1 Q07820 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
MAOA P21397 5/20 0.39
MAPT P10636 4/20 0.36
KDM4E B2RXH2 2/20 0.36
POLB P06746 2/20 0.36
GAA P10253 2/20 0.36
CDK2 P24941 2/20 0.35
PTGES O14684 1/20 0.35
THRB P10828 3/20 0.34
HPGD P15428 2/20 0.34
ALOX15 P16050 2/20 0.34
SNCA P37840 2/20 0.34
RECQL P46063 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27577308 0.82 ALDH1A1 (0.36) MEN1ALDH1A1KMT2ADNMT1CACNA1B
Hydrochloric Acid SCHEMBL8689070 0.79 SLC9A1 (0.38)
SCHEMBL9120063 0.77 NPC1 (0.59) MAOAMAPTKDM4EHSD17B10CYP1A2
SCHEMBL2825515 0.74 KMT2A (0.51) MEN1ALDH1A1KMT2AMAPTKDM4E
SCHEMBL16292878 0.69 KDM4E (0.38) MEN1ALDH1A1KMT2AKDM4EGAA
Bicarbonate SCHEMBL11662741 0.68 KMT2A (0.52) MEN1ALDH1A1KMT2ADNMT1CACNA1B
SCHEMBL4222641 0.67 ALB (0.39) MEN1KMT2AMAOAKDM4EALOX15
SCHEMBL70219 0.66 ALDH1A1 (0.62) MEN1ALDH1A1KMT2ADNMT1CACNA1B
SCHEMBL29363189 0.66 ALDH1A1 (0.62) MEN1ALDH1A1KMT2ADNMT1CACNA1B
SCHEMBL8291486 0.65 KDM4E (0.43) MEN1ALDH1A1KMT2ADNMT1CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59190985-A None JP disclosed
JP-S59190985-A BISBENZOFURAN DERIVATIVE AND ITS PREPARATION KAKEN PHARMACEUT CO LTD 1984-10-29 JP disclosed