Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300707 | 0.77 | NPC1 (0.56) | KDM4EHSD17B10KMT2ASMN1; SMN2LMNA | |
| SCHEMBL13115673 | 0.75 | KDM4E (0.48) | TP53KDM4EHSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL13115671 | 0.74 | KDM4E (0.56) | TP53KDM4EHSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL17322839 | 0.74 | KDM4E (0.69) | KDM4EHSD17B10KMT2ASMN1; SMN2LMNA | |
| SCHEMBL22844066 | 0.72 | TP53 (0.45) | TP53KMT2ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL24779602 | 0.71 | ALDH1A1 (0.64) | TP53KMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL31602911 | 0.70 | MEN1 (0.56) | TP53KDM4EHSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL13644161 | 0.70 | KDM4E (0.46) | TP53KDM4EHSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL3707494 | 0.70 | NOTUM (0.53) | TP53KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL1169685 | 0.70 | RECQL (0.60) | TP53HSD17B10SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59098060-A | — | — | None | — | — | JP | disclosed |
| JP-S5998060-A | INDAZOLE DERIVATIVE, ITS PREPARATION AND AGRICULTURAL CHEMICAL | FUJISAWA PHARMACEUT CO LTD | 1984-06-06 | — | — | JP | disclosed |