Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CCR1 | P32246 | 3/20 | 0.53 |
| ▸ | CCR5 | P51681 | 3/20 | 0.53 |
| ▸ | CCR8 | P51685 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275424 | 0.82 | PDE10A (0.60) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL3671369 | 0.80 | ALDH1A1 (0.62) | KDM4ETP53SMN1; SMN2LMNAHSP90AA1 | |
| SCHEMBL11036012 | 0.79 | KDM4E (0.70) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| Bromide SCHEMBL14988938 | 0.77 | ALDH1A1 (0.68) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL9560121 | 0.73 | DYRK1A (0.50) | KDM4ETP53SMN1; SMN2LMNACYP1A2 | |
| Terpyridine SCHEMBL57442 | 0.71 | KDM4E (1.00) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL30172832 | 0.71 | KDM4E (1.00) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| Terpyridine SCHEMBL29357603 | 0.71 | KDM4E (1.00) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| SCHEMBL7964803 | 0.71 | KDM4E (1.00) | KDM4ETP53SMN1; SMN2LMNACCR1 | |
| Dipyridyl SCHEMBL3711450 | 0.71 | KDM4E (1.00) | KDM4ETP53SMN1; SMN2LMNACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551530-A | HYPOTENSIVE, TRANQUILIZER | AMERICAN CYANAMID COMPANY (US) | 1985-11-05 | — | — | US | disclosed |