Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560121 | 0.85 | DYRK1A (0.50) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL17626883 | 0.82 | RAB9A (0.62) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL2904195 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL1829674 | 0.80 | KMO (0.47) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL17626904 | 0.80 | KMO (0.47) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL11036010 | 0.80 | KDM4E (0.53) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL3671367 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL17626896 | 0.76 | JAK2 (0.40) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL11475707 | 0.73 | HPGD (0.44) | ALDH1A1KDM4EHPGDGLAHSD17B10 | |
| SCHEMBL7224646 | 0.73 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDGLAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2237788-A2 | AEROSOLIZED NITRITE AND NITRIC OXIDE - DONATING COMPOUNDS AND USES THEREOF | Aires Pharmaceuticals, Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009086470-A2 | AEROSOLIZED NITRITE AND NITRIC OXIDE - DONATING COMPOUNDS AND USES THEREOF | AIRES PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| US-5037980-A | Anxiolytic agents, hypotensive agents | AMERICAN CYANAMID COMPANY (US) | 1991-08-06 | — | — | US | disclosed |