SCHEMBL11036013

SCHEMBL11036013

Cc1c(O)ccc(O)c1C.Oc1ccc(O)c(Cl)c1Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.57
MAPK1 P28482 2/20 0.57
TSHR P16473 3/20 0.42
TRPA1 O75762 2/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 2/20 0.38
GAA P10253 2/20 0.38
MAPT P10636 1/20 0.38
ESR2 Q92731 6/20 0.38
ESR1 P03372 5/20 0.38
HSD17B10 Q99714 2/20 0.38
HSP90AA1 P07900 1/20 0.38
HPGD P15428 1/20 0.38
CHRM1 P11229 1/20 0.38
ALOX15 P16050 1/20 0.38
MAOA P21397 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3792759 0.88 MAPK1 (0.50) CYP3A4MAPK1TSHRTRPA1ATM
SCHEMBL68013 0.84 TRPA1 (0.53) CYP3A4MAPK1TRPA1ATMALDH1A1
SCHEMBL68064 0.84 CYP3A4 (0.75) CYP3A4MAPK1TSHRALDH1A1MAPT
SCHEMBL31392414 0.84 CYP3A4 (0.75) CYP3A4MAPK1TSHRALDH1A1MAPT
SCHEMBL29457565 0.84 TRPA1 (0.53) CYP3A4MAPK1TRPA1ATMALDH1A1
SCHEMBL7743436 0.84 CYP3A4 (0.75) CYP3A4MAPK1TSHRALDH1A1MAPT
SCHEMBL335595 0.80 CYP3A4 (0.48) CYP3A4MAPK1TSHRTRPA1ATM
SCHEMBL9849381 0.80 CYP3A4 (0.55) CYP3A4MAPK1TSHRTRPA1ALDH1A1
SCHEMBL29566553 0.80 CYP3A4 (0.48) CYP3A4MAPK1TSHRTRPA1ATM
SCHEMBL1157142 0.78 CYP3A4 (0.46) CYP3A4MAPK1TSHRTRPA1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0156600-A1 Composite fiber blends CELANESE CORPORATION (US) 1985-10-02 EP disclosed