SCHEMBL9849381

SCHEMBL9849381

Cc1ccc(O)c(Cl)c1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.55
MAPK1 P28482 2/20 0.55
ALOX15 P16050 2/20 0.42
CHRM1 P11229 1/20 0.42
MAOA P21397 1/20 0.42
TBXA2R P21731 1/20 0.42
ADRA1A P35348 1/20 0.42
HTR2B P41595 1/20 0.42
TSHR P16473 3/20 0.40
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TTR P02766 1/20 0.40
ESR2 Q92731 4/20 0.38
CASP1 P29466 1/20 0.37
PDE10A Q9Y233 1/20 0.37
ESR1 P03372 4/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29403294 0.82 CYP3A4 (0.41) CYP3A4MAPK1ALOX15CHRM1MAOA
SCHEMBL31392414 0.82 CYP3A4 (0.75) CYP3A4MAPK1ALOX15TSHRTDP1
SCHEMBL68064 0.82 CYP3A4 (0.75) CYP3A4MAPK1ALOX15TSHRTDP1
SCHEMBL7743436 0.82 CYP3A4 (0.75) CYP3A4MAPK1ALOX15TSHRTDP1
SCHEMBL477584 0.82 CYP3A4 (0.41) CYP3A4MAPK1ALOX15CHRM1MAOA
SCHEMBL3787501 0.81 CYP3A4 (0.46) CYP3A4MAPK1ALOX15CHRM1MAOA
SCHEMBL1157142 0.81 CYP3A4 (0.46) CYP3A4MAPK1ALOX15CHRM1MAOA
SCHEMBL3684343 0.81 TRPA1 (0.44) CYP3A4MAPK1ALOX15CHRM1MAOA
SCHEMBL29735281 0.81 ALDH1A1 (0.45) CYP3A4MAPK1ALOX15CHRM1MAOA
SCHEMBL768320 0.81 ALDH1A1 (0.45) CYP3A4MAPK1ALOX15CHRM1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9161542-B2 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2015-10-20 US claimed
WO-2012162595-A2 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2012-11-29 WO claimed
US-20120302611-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS DOW AGROSCIENCES LLC (US) 2012-11-29 US claimed
US-4429163-A CATALYTIC OXIDATION OF A P-CRESOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-01-31 US claimed
US-4410737-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US claimed
US-4410738-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US claimed
US-4410739-A LEWIS ACID, NOBLE METAL CATALYST RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US claimed
CN-113403155-B Preparation method of crystal soap 浙江大学 2023-04-18 CN disclosed
CN-113416617-A Transparent soap key isolation rubber pad 杭州微冠科技有限公司 2021-09-21 CN disclosed
CN-113403155-A Preparation method of crystal soap 浙江大学 2021-09-17 CN disclosed
CN-104080839-B The manufacture method and polycarbonate resin particulate of polycarbonate resin particulate 东丽株式会社 2017-11-21 CN disclosed
US-9199927-B2 Guanidinobenzoic acid compound ASTELLAS PHARMA INC. (JP) 2015-12-01 US disclosed
US-9161542-B2 Pesticidal compositions and related methods DOW AGROSCIENCES LLC (US) 2015-10-20 US disclosed
EP-0161484-B1 ESSENTIALLY ORTHO-LINKED POLY(ARYL ETHERS) BAYER AG (DE) 1988-09-21 EP disclosed
US-4705843-A Process for the production of substituted polyaryl ethers BAYER AKTIENGESELLSCHAFT (DE) 1987-11-10 US disclosed
EP-0161484-A1 Essentially ortho-linked poly(aryl ethers) BAYER AG (DE) 1985-11-21 EP disclosed
US-4540834-A HYDRODECHLORINATION OF POLYCHLOROPHENOL, HYDRIOTIC ACID RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-09-10 US disclosed
US-4410737-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US disclosed
US-4410738-A Preparation of meta-chlorophenols by selective hydrodechlorination of polychlorophenols RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US disclosed
US-4410739-A LEWIS ACID, NOBLE METAL CATALYST RHONE-POULENC INDUSTRIES (FR) 1983-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120302611-A1 PESTICIDAL COMPOSITIONS AND RELATED METHODS PRDX6, PRDX2, PRDX1 CYP3A4 1276/4885MAPK1 4778/4885ALOX15 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.