Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11036061 | 1.00 | CYP19A1 (0.47) | CYP19A1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL10940638 | 0.76 | CYP19A1 (0.53) | CYP19A1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL11243013 | 0.74 | CYP19A1 (0.51) | CYP19A1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL9729237 | 0.74 | CYP19A1 (0.51) | CYP19A1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL10946336 | 0.72 | CYP19A1 (0.53) | CYP19A1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL10940175 | 0.71 | CYP19A1 (0.50) | CYP19A1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL6442620 | 0.70 | CYP19A1 (0.55) | CYP19A1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL11043342 | 0.70 | MAPT (0.37) | CYP19A1KMT2AHSP90AA1LMNAMAPT | |
| SCHEMBL8927087 | 0.68 | CYP19A1 (0.41) | CYP19A1KMT2AKDM4EMEN1GAA | |
| SCHEMBL8927085 | 0.68 | CYP19A1 (0.41) | CYP19A1KMT2AKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148026-A2 | Fungicidal imidazoles and triazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-10 | — | — | EP | disclosed |