Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505307 | 0.76 | CYP19A1 (0.42) | MAPTSMN1; SMN2ALDH1A1CYP19A1EGLN3 | |
| SCHEMBL4433009 | 0.70 | — | — | |
| SCHEMBL665120 | 0.66 | — | — | |
| SCHEMBL5657617 | 0.65 | CYP19A1 (0.48) | MAPTSMN1; SMN2ALDH1A1CYP19A1EGLN3 | |
| SCHEMBL10939904 | 0.63 | CYP1A2 (0.44) | MAPTSMN1; SMN2ALDH1A1CYP19A1HSP90AA1 | |
| SCHEMBL45842 | 0.63 | — | — | |
| SCHEMBL1792499 | 0.63 | — | — | |
| SCHEMBL473431 | 0.63 | — | — | |
| SCHEMBL9517698 | 0.62 | FDPS (0.50) | ALDH1A1CYP19A1EGLN3UGT1A4PDE4D | |
| SCHEMBL25088374 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148026-A2 | Fungicidal imidazoles and triazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-10 | — | — | EP | disclosed |