Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13491150 | 0.81 | EPHX1 (0.56) | SMN1; SMN2CNR1L3MBTL1EPHX1MTNR1A | |
| SCHEMBL25658419 | 0.79 | EPHX1 (0.43) | PKMSMN1; SMN2CNR1ALDH1A1LMNA | |
| SCHEMBL11000515 | 0.75 | EPHX1 (0.50) | SMN1; SMN2GAALMNASLC6A3CHRM1 | |
| SCHEMBL4262200 | 0.74 | LMNA (0.66) | PKMSMN1; SMN2CNR1KDM4EALDH1A1 | |
| SCHEMBL8895206 | 0.74 | PDPK1 (0.43) | PKMSMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL11361146 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1GAALMNASLC6A3 | |
| SCHEMBL11611303 | 0.73 | SMN1; SMN2 (0.54) | PKMSMN1; SMN2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL777788 | 0.70 | LMNA (0.44) | LMNASLC6A3 | |
| SCHEMBL12774635 | 0.70 | SLC6A3 (0.56) | LMNASLC6A3 | |
| SCHEMBL13389213 | 0.69 | LMNA (0.58) | SMN1; SMN2ALDH1A1GAAL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517192-A | 6-Alkyl-5-[4-(alkylsulfinyl or alkylsulfonyl)phenyl]-2(1H)-pyridinones and their use as cardiatonics | STERLING DRUG INC. (US) | 1985-05-14 | — | — | US | disclosed |