Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11036594 | 1.00 | CYP24A1 (0.56) | CYP24A1MAPTRAB9AHTTNPC1 | |
| SCHEMBL11145976 | 0.83 | CYP24A1 (0.58) | CYP24A1MAPTRAB9AHTTNPC1 | |
| SCHEMBL11145979 | 0.83 | CYP24A1 (0.58) | CYP24A1MAPTRAB9AHTTNPC1 | |
| SCHEMBL11136053 | 0.81 | CYP24A1 (0.56) | CYP24A1MAPTRAB9AHTTNPC1 | |
| SCHEMBL11136051 | 0.81 | CYP24A1 (0.56) | CYP24A1MAPTRAB9AHTTNPC1 | |
| SCHEMBL564925 | 0.75 | MAPT (0.45) | CYP24A1MAPTHTTSMN1; SMN2MITF | |
| SCHEMBL4814945 | 0.75 | MAPT (0.45) | CYP24A1MAPTHTTSMN1; SMN2MITF | |
| SCHEMBL564926 | 0.75 | MAPT (0.45) | CYP24A1MAPTHTTSMN1; SMN2MITF | |
| SCHEMBL11436892 | 0.75 | CYP24A1 (0.73) | CYP24A1MAPTRAB9AHTTNPC1 | |
| Dimethylformamide SCHEMBL9937733 | 0.73 | ALDH1A1 (0.38) | CYP24A1MAPTHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115640-A2 | Substituted 4-imidazolyl-pyrazoles, process for their preparation and medicaments containing them | BAYER AG (DE) | 1984-08-15 | — | — | EP | disclosed |
| EP-0041615-B1 | USE OF IMIDAZOLYL-VINYL KETONES AND ALCOHOLS AS ANTIMICROBIAL AGENTS | BAYER AG (DE) | 1984-02-22 | — | — | EP | disclosed |
| EP-0040366-B1 | IMIDAZOLYL-VINYL KETONES AND CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1983-11-02 | — | — | EP | disclosed |
| US-4385061-A | Combating fungi with imidazolyl-vinyl ketones and carbinols | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-24 | — | — | US | disclosed |
| US-4380628-A | REACTING THE KETO-ENAMINE-SUBSTITUTED IMIDAZOLE OR 1,2,4-TRIAZOLE DERIVATIVE WITH A GINR ARD REAGENT; FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-04-19 | — | — | US | disclosed |
| EP-0032239-B1 | METHOD FOR PREPARING AZOLYL-VINYL-KETONES | BAYER AG (DE) | 1983-01-12 | — | — | EP | disclosed |
| EP-0032239-A1 | Method for preparing azolyl-vinyl-ketones | BAYER AG (DE) | 1981-07-22 | — | — | EP | disclosed |