Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1325 | 0.83 | FAAH (0.45) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL15846673 | 0.83 | FAAH (0.45) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL2194853 | 0.81 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL10814524 | 0.81 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| Hydrochloric Acid SCHEMBL6226784 | 0.81 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLNFKB1 | |
| Hydrogen Sulfide SCHEMBL10814521 | 0.81 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| Phosphine SCHEMBL31680518 | 0.81 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| Methylene Chloride SCHEMBL4130957 | 0.75 | ALDH1A1 (0.42) | ALDH1A1LMNAFAAHMGLLMAPT | |
| SCHEMBL2610160 | 0.75 | FAAH (0.41) | ALDH1A1LMNAFAAHMGLLCYP24A1 | |
| SCHEMBL7736262 | 0.75 | FAAH (0.44) | ALDH1A1LMNAFAAHMGLLCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652153-A2 | DNA SEQUENCING BY SYNTHESIS USING MODIFIED NUCLEOTIDES AND NANOPORE DETECTION | The Trustees of Columbia University in the City of New York (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012083249-A2 | DNA SEQUENCING BY SYNTHESIS USING MODIFIED NUCLEOTIDES AND NANOPORE DETECTION | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-06-21 | — | — | WO | disclosed |