SCHEMBL11036628

SCHEMBL11036628

CCOC(=O)c1ccc2c(c1N)C(=O)c1ccccc1C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.62
ALDH1A1 P00352 9/20 0.62
MAPK1 P28482 6/20 0.62
MEN1 O00255 5/20 0.62
KMT2A Q03164 5/20 0.62
LMNA P02545 3/20 0.62
THRB P10828 3/20 0.62
POLB P06746 3/20 0.62
RECQL P46063 1/20 0.62
SMN1; SMN2 Q16637 5/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
HTT P42858 1/20 0.55
CYP3A4 P08684 4/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
TSHR P16473 2/20 0.55
HBB P68871 2/20 0.55
CASP3 P42574 1/20 0.55
SENP7 Q9BQF6 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23199089 0.84 MAPT (0.76) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL8941856 0.84 MAPT (0.71) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL19125588 0.82 THRB (0.64) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL11420252 0.80 MAPT (0.49) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL13800968 0.80 MAPT (0.68) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL31670390 0.80 MAPT (0.68) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL8744278 0.79 MAPT (0.73) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL11327907 0.79 SMN1; SMN2 (0.67) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL5846611 0.79 MAPT (0.58) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL92418 0.78 MAPT (0.47) MAPTALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0134198-A1 Use of quinone derivatives for the protection of cultivated plants against the phytotoxic effects of herbicides CIBA-GEIGY AG (CH) 1985-03-13 EP claimed
EP-0134198-A1 Use of quinone derivatives for the protection of cultivated plants against the phytotoxic effects of herbicides CIBA-GEIGY AG (CH) 1985-03-13 EP disclosed