SCHEMBL8941856

SCHEMBL8941856

COC(=O)c1ccc2c(c1N)C(=O)c1ccccc1C2=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.71
MITF O75030 1/20 0.71
ALDH1A1 P00352 7/20 0.68
MAPK1 P28482 6/20 0.68
MEN1 O00255 6/20 0.68
KMT2A Q03164 6/20 0.68
THRB P10828 3/20 0.68
POLB P06746 3/20 0.68
LMNA P02545 2/20 0.68
RECQL P46063 1/20 0.68
SMN1; SMN2 Q16637 5/20 0.55
NPC1 O15118 4/20 0.55
RAB9A P51151 4/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
PKM P14618 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
CYP3A4 P08684 2/20 0.55
MCL1 Q07820 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
TSHR P16473 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11036628 0.84 MAPT (0.62) MAPTMITFALDH1A1MAPK1MEN1
SCHEMBL10391553 0.84 MAPT (0.74) MAPTMITFALDH1A1MAPK1MEN1
SCHEMBL68969 0.83 MAPT (0.73) MAPTMITFALDH1A1MAPK1MEN1
SCHEMBL28318060 0.83 MAPT (0.73) MAPTMITFALDH1A1MAPK1MEN1
SCHEMBL8744278 0.83 MAPT (0.73) MAPTMITFALDH1A1MAPK1MEN1
SCHEMBL3795391 0.81 MAPT (0.62) MAPTMITFALDH1A1MAPK1MEN1
SCHEMBL2839419 0.81 MAPT (1.00) MAPTMITFALDH1A1MAPK1MEN1
SCHEMBL8757428 0.81 MAPT (0.69) MAPTMITFALDH1A1MAPK1MEN1
SCHEMBL8941899 0.81 MAPT (0.76) MAPTMITFALDH1A1MAPK1MEN1
SCHEMBL6834609 0.81 MAPT (0.68) MAPTMITFALDH1A1MAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-5559216-A AZO COUPLING HOECHST AG (DE) 1996-09-24 US disclosed
US-5493011-A PIGMENTING HIGH MOLECULAR WEIGHT NATURAL OR SYNTHETIC ORGANIC MATERIALS HOECHST AG (DE) 1996-02-20 US disclosed
US-5026831-A Water-insoluble disazo colorants having hetero-bicyclic methylene-active compounds as coupling component HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-25 US disclosed
US-4709019-A COLORFAST PIGMENTS BAYER AKTIENGESELLSCHAFT (DE) 1987-11-24 US disclosed
US-4389215-A Anthraquinone-azomethine compounds, processes for their preparation and processes for dyeing synthetic fibre materials and for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1983-06-21 US disclosed
US-4323671-A Anthraquinone derivatives, processes for their preparation, processes for pigmenting organic macromolecular substances, and pigmented organic macromolecular material BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
US-4323670-A Anthraquinone-azomethine compounds, processes for their preparation and processes for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
US-4319025-A Anthraquinone-azomethine compounds, processes for their preparation and processes for dyeing synthetic fibre materials and for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4309221-A ORGANIC PIGMENTS FOR MACROMOLECULAR SUBSTANCES;GOOD FASTNESS AND HEAT RESISTANCE BAYER AKTIENGESELLSCHAFT (DE) 1982-01-05 US disclosed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US disclosed
US-4284411-A CONDENSATION, PIGMENTING BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed