Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19446139 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL6825821 | 0.86 | ALDH1A1 (0.64) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL16485594 | 0.85 | PSIP1 (0.46) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL14491377 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL14299263 | 0.78 | ALDH1A1 (0.59) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL10725680 | 0.77 | CA12 (0.38) | ALDH1A1CYP2C19CYP3A4CYP2C9LMNA | |
| SCHEMBL11363256 | 0.77 | PSEN1 (0.41) | ALDH1A1CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL10759972 | 0.77 | CA12 (0.38) | ALDH1A1CYP2C19CYP3A4CYP2C9LMNA | |
| SCHEMBL3581029 | 0.77 | CA12 (0.38) | ALDH1A1CYP2C19CYP3A4CYP2C9LMNA | |
| SCHEMBL9485780 | 0.77 | CA12 (0.38) | ALDH1A1CYP2C19CYP3A4CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124577-A1 | NEW CHELATE FORMING QUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS | HÖGBERG, Sverker (SE) | 1984-11-14 | — | — | EP | disclosed |
| WO-1984001947-A1 | NEW CHELATE FORMING QUINOLINE COMPOUNDS AND PROCESSES FOR RECOVERING METALS | HOEGBERG SVERKER | 1984-05-24 | — | — | WO | disclosed |