Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.58 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.58 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.58 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.58 |
| ▸ | NAAA | Q02083 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18126611 | 0.89 | MAPT (0.66) | PLAAT3PLAAT5PLAAT2PLAAT4NAAA | |
| SCHEMBL7829175 | 0.87 | SMN1; SMN2 (0.67) | PLAAT3PLAAT5PLAAT2PLAAT4NAAA | |
| SCHEMBL8170713 | 0.87 | NAAA (0.58) | PLAAT3PLAAT5PLAAT2PLAAT4NAAA | |
| SCHEMBL19612671 | 0.85 | NAAA (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4NAAA | |
| SCHEMBL19612688 | 0.83 | NAAA (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4NAAA | |
| SCHEMBL8511630 | 0.83 | MAPT (0.71) | PLAAT3PLAAT5PLAAT2PLAAT4SMN1; SMN2 | |
| SCHEMBL31567921 | 0.82 | TAAR1 (0.65) | PLAAT3PLAAT5PLAAT2PLAAT4NAAA | |
| SCHEMBL5024832 | 0.81 | SMN1; SMN2 (0.68) | PLAAT3PLAAT5PLAAT2PLAAT4NAAA | |
| SCHEMBL10420235 | 0.81 | HDAC3 (0.60) | PLAAT3PLAAT5PLAAT2PLAAT4NAAA | |
| SCHEMBL11041224 | 0.81 | HDAC3 (0.60) | PLAAT3PLAAT5PLAAT2PLAAT4NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038343-B1 | SUBSTITUTED CARBOXYLIC CETO-ACIDS, PROCESS FOR THE PREPARATION THEREOF, USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-12-27 | — | — | EP | disclosed |
| US-4334089-A | HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT (DE) | 1982-06-08 | — | — | US | disclosed |
| EP-0051077-A1 | Substituted oxocarboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-05-12 | — | — | EP | disclosed |
| EP-0038343-A1 | SUBSTITUTED CARBOXYLIC CETO-ACIDS, PROCESS FOR THE PREPARATION THEREOF, USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM. | BYK GULDEN LOMBERG CHEM FAB (DE) | 1981-10-28 | — | — | EP | disclosed |
| WO-1981001285-A1 | SUBSTITUTED CARBOXYLIC CETO-ACIDS,PROCESS FOR THE PREPARATION THEREOF,USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1981-05-14 | — | — | WO | disclosed |