Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | TP53 | P04637 | 7/20 | 0.60 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037107 | 0.92 | MAPT (0.68) | MAPTTP53THRBSMN1; SMN2POLB | |
| SCHEMBL11035096 | 0.88 | MAPT (0.60) | MAPTTP53THRBSMN1; SMN2POLB | |
| SCHEMBL11011840 | 0.88 | MAPT (0.60) | MAPTTP53THRBSMN1; SMN2POLB | |
| SCHEMBL11012567 | 0.82 | TP53 (0.57) | MAPTTP53THRBSMN1; SMN2RXFP1 | |
| SCHEMBL14875121 | 0.81 | F2RL3 (0.46) | MAPTTP53THRBSMN1; SMN2POLB | |
| SCHEMBL11011832 | 0.79 | MAPT (0.69) | MAPTTP53THRBSMN1; SMN2POLB | |
| SCHEMBL11035275 | 0.79 | MAPT (0.59) | MAPTTP53THRBSMN1; SMN2POLB | |
| SCHEMBL11035093 | 0.79 | MAPT (0.73) | MAPTTP53THRBSMN1; SMN2POLB | |
| SCHEMBL11222994 | 0.78 | HSD17B10 (0.48) | MAPTTP53THRBSMN1; SMN2KDM4E | |
| SCHEMBL31338680 | 0.77 | MAPT (0.66) | MAPTTP53THRBSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |