Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222988 | 0.90 | HSD17B10 (0.56) | HSD17B10TP53MAPTPDE11ATHRB | |
| SCHEMBL6703523 | 0.79 | PARP15 (0.49) | TP53MAPTTHRBKDM4EALDH1A1 | |
| SCHEMBL11011840 | 0.78 | MAPT (0.60) | TP53MAPTTHRBKDM4EALDH1A1 | |
| SCHEMBL11037111 | 0.78 | MAPT (0.60) | TP53MAPTTHRBKDM4EALDH1A1 | |
| SCHEMBL17621004 | 0.77 | THRB (0.41) | MAPTTHRBPPARA | |
| SCHEMBL17620857 | 0.76 | TP53 (0.64) | TP53MAPTTHRBKDM4EALDH1A1 | |
| SCHEMBL17621065 | 0.75 | SRD5A2 (0.49) | TP53MAPTTHRBTSHRSMN1; SMN2 | |
| SCHEMBL18548699 | 0.75 | TP53 (0.43) | HSD17B10TP53MAPTKDM4ETSHR | |
| SCHEMBL29660211 | 0.75 | TP53 (0.43) | HSD17B10TP53MAPTKDM4ETSHR | |
| SCHEMBL17621014 | 0.73 | RAB9A (0.41) | HSD17B10TP53MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57149288-A | — | — | None | — | — | JP | disclosed |
| JP-S57149288-A | IMIDAZO(2,1-B)BENZOTHIAZOLE DERIVATIVE | YAMANOUCHI PHARMACEUT CO LTD | 1982-09-14 | — | — | JP | disclosed |