Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034478 | 0.79 | DNM1 (0.40) | DNM1TSHRTHRBALDH1A1CA12 | |
| SCHEMBL13152919 | 0.74 | DNM1 (0.46) | DNM1TSHRTHRBALDH1A1CA12 | |
| SCHEMBL14997774 | 0.72 | DNM1 (0.50) | DNM1TSHRTHRBALDH1A1CA12 | |
| SCHEMBL14997773 | 0.72 | DNM1 (0.50) | DNM1TSHRTHRBALDH1A1CA12 | |
| Nonane SCHEMBL28466423 | 0.72 | DNM1 (0.50) | DNM1TSHRTHRBALDH1A1CA12 | |
| SCHEMBL22532181 | 0.72 | DNM1 (0.43) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL12243063 | 0.72 | DNM1 (0.43) | DNM1TSHRTHRBALDH1A1CA12 | |
| SCHEMBL10705836 | 0.72 | DNM1 (0.50) | DNM1TSHRTHRBALDH1A1CA12 | |
| SCHEMBL7940648 | 0.72 | DNM1 (0.43) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL28190831 | 0.72 | DNM1 (0.50) | DNM1TSHRTHRBALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052842-B1 | N,N-DIARYL CARBAMOYL FLUORIDES, PROCESS FOR PREPARING THEM AND THEIR USE IN THE PREPARATION OF UREAS, AND THE UREAS OBTAINED THEREBY | BAYER AG (DE) | 1985-09-18 | — | — | EP | claimed |