Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 8/20 | 0.36 |
| ▸ | CES1 | P23141 | 5/20 | 0.34 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4605368 | 0.97 | DNM1 (0.48) | DNM1TSHRTHRBFAAHCES1 | |
| SCHEMBL1335502 | 0.92 | DNM1 (0.33) | DNM1TSHRTHRBFAAHCES1 | |
| SCHEMBL22532181 | 0.83 | DNM1 (0.43) | DNM1TSHRTHRBFAAHCES1 | |
| SCHEMBL4603555 | 0.79 | CA1 (0.30) | CA1 | |
| SCHEMBL11034478 | 0.79 | DNM1 (0.40) | DNM1TSHRTHRBFAAHCES1 | |
| SCHEMBL18387850 | 0.76 | DNM1 (0.42) | DNM1TSHRTHRBFAAHCA12 | |
| SCHEMBL13152919 | 0.74 | DNM1 (0.46) | DNM1TSHRTHRBCA12CA1 | |
| SCHEMBL6563163 | 0.74 | DNM1 (0.33) | DNM1TSHRTHRBFAAHCES1 | |
| SCHEMBL28928935 | 0.74 | DNM1 (0.40) | DNM1TSHRTHRBCES2CA12 | |
| SCHEMBL11037240 | 0.72 | DNM1 (0.43) | DNM1TSHRTHRBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |