⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491548 | 0.70 | — | — | |
| SCHEMBL9777662 | 0.70 | — | — | |
| SCHEMBL9823953 | 0.70 | — | — | |
| SCHEMBL11037243 | 0.66 | — | — | |
| SCHEMBL9071864 | 0.62 | L3MBTL1 (0.34) | — | |
| SCHEMBL7106992 | 0.61 | — | — | |
| SCHEMBL6371601 | 0.61 | — | — | |
| SCHEMBL10745821 | 0.61 | — | — | |
| SCHEMBL10763563 | 0.60 | — | — | |
| SCHEMBL7292397 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160502-B1 | Improvements in and relating to octahydrothiazolo[4,5-g]quinolines | ELI LILLY AND COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0160502-B1 | Improvements in and relating to octahydrothiazolo[4,5-g]quinolines | ELI LILLY AND COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0171277-A2 | Improvements in or relating to tricycling quinoline derivatives | ELI LILLY AND COMPANY (US) | 1986-02-12 | — | — | EP | disclosed |
| EP-0160502-A2 | Improvements in and relating to octahydrothiazolo[4,5-g]quinolines | ELI LILLY AND COMPANY (US) | 1985-11-06 | — | — | EP | disclosed |
| EP-0160502-A2 | Improvements in and relating to octahydrothiazolo[4,5-g]quinolines | ELI LILLY AND COMPANY (US) | 1985-11-06 | — | — | EP | disclosed |
| US-4537964-A | Method of preparing permissibly-substituted 1H(and 2H)pyrazolo[3,4-g]quinolines; pyrimido[4,5,g]quinolines; thiazolo[4,5,g]quinolines and intermediates therefore | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| US-4537893-A | TREATMENT OF PARKINSONS DISEASE, SEXUAL DYFUNCTION, ANXIETY, DEPRESSION OR HYPERTENSION | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| US-4537893-A | TREATMENT OF PARKINSONS DISEASE, SEXUAL DYFUNCTION, ANXIETY, DEPRESSION OR HYPERTENSION | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| US-4537893-A | TREATMENT OF PARKINSONS DISEASE, SEXUAL DYFUNCTION, ANXIETY, DEPRESSION OR HYPERTENSION | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |