Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21723616 | 0.82 | GAA (0.50) | ALDH1A1MAPTMEN1NPC1RAB9A | |
| SCHEMBL2929136 | 0.81 | NPSR1 (0.51) | ALDH1A1MAPTMEN1NPC1RAB9A | |
| SCHEMBL9864596 | 0.78 | ALDH1A1 (0.59) | RORCTGM2ALDH1A1MAPTMEN1 | |
| SCHEMBL22719492 | 0.78 | KMT2A (0.62) | RORCTGM2ALDH1A1MAPTMEN1 | |
| SCHEMBL9681922 | 0.78 | ALDH1A1 (0.59) | TGM2ALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL18256222 | 0.78 | ALDH1A1 (0.56) | RORCTGM2ALDH1A1MAPTMEN1 | |
| SCHEMBL29505028 | 0.78 | KMT2A (0.62) | RORCTGM2ALDH1A1MAPTMEN1 | |
| SCHEMBL22807394 | 0.78 | ALDH1A1 (0.71) | TGM2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL17368531 | 0.78 | HTT (0.60) | TGM2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5203193 | 0.74 | GAA (0.55) | ALDH1A1MAPTMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4510140-A | HYPOTENSIVE AGENTS; ANTHIHISTAMINES; ANALGESICS; SEDATIVES | RECORDATI S.A. (CH) | 1985-04-09 | — | — | US | disclosed |
| EP-0074768-A2 | Alkanoylanilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1983-03-23 | — | — | EP | disclosed |