Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GALR2 | O43603 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203193 | 0.93 | GAA (0.55) | NPSR1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL11237157 | 0.91 | POLB (0.60) | NPSR1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL10936842 | 0.90 | MAPT (0.55) | NPSR1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL14903460 | 0.88 | RECQL (0.57) | NPSR1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL29725300 | 0.88 | RECQL (0.57) | NPSR1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL21723616 | 0.88 | GAA (0.50) | ALDH1A1SMN1; SMN2MAPTLMNAGAA | |
| SCHEMBL11525234 | 0.85 | SLC9A1 (0.50) | NPSR1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL4149265 | 0.85 | LMNA (0.48) | NPSR1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL11638099 | 0.85 | POLB (0.48) | NPSR1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL2972082 | 0.85 | SLC9A1 (0.60) | NPSR1ALDH1A1SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3625215-B1 | FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS | PI INDUSTRIES LTD (IN) | 2023-09-13 | — | — | EP | disclosed |
| US-20200148635-A1 | FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS | PI INDUSTRIES LTD. (IN) | 2020-05-14 | — | — | US | disclosed |
| US-20200148635-A1 | FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS | PI INDUSTRIES LTD. (IN) | 2020-05-14 | — | — | US | disclosed |
| EP-3625215-A1 | FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS | PI Industries Ltd (IN) | 2020-03-25 | — | — | EP | disclosed |
| CN-110770210-A | Novel amidine compounds | PI工业有限公司 | 2020-02-07 | — | — | CN | disclosed |
| WO-2018211442-A1 | FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS | PI INDUSTRIES LTD. (IN) | 2018-11-22 | — | — | WO | disclosed |
| EP-2229377-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | Wyeth LLC (US) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | disclosed |
| US-4151203-A | Process for the preparation of p-nitroaniline compounds by the alkaline hydrolysis of mixed anilides | EASTMAN KODAK COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148635-A1 | FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS | PADI4, PADI1, PADI2 | NPSR1 2530/4885ALDH1A1 2717/4885SMN1; SMN2 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.