SCHEMBL11037451

SCHEMBL11037451

C=CCC1COCCN1CC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 4/20 0.35
PDK2 Q15119 1/20 0.33
PDK3 Q15120 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16767724 0.84 PDK1 (0.34) PDK1PDK2PDK3
SCHEMBL25125561 0.79 PDK1 (0.39) PDK1PDK2PDK3
SCHEMBL890074 0.79 PDK1 (0.39) PDK1PDK2PDK3
SCHEMBL1700062 0.76 PDK1 (0.51) PDK1PDK2PDK3
Hydrochloric Acid SCHEMBL31393754 0.76 PDK1 (0.37) PDK1PDK2PDK3
SCHEMBL17778486 0.76 PDK1 (0.51) PDK1PDK2PDK3
SCHEMBL24630698 0.76 PDK1 (0.51) PDK1PDK2PDK3
SCHEMBL1806182 0.76 PDK1 (0.37) PDK1PDK2PDK3
SCHEMBL6531860 0.74 PDK1 (0.35) PDK1PDK2PDK3
SCHEMBL462090 0.74 CHRNB2 (0.32) PDK1CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170340770-A1 HYDRAULIC CEMENT-BASED IMPLANT MATERIAL AND USE THEREOF INNOTERE GMBH (DE) 2017-11-30 US disclosed
US-9764057-B2 Hydraulic cement-based implant material and use thereof INNOTERE GMBH (DE) 2017-09-19 US disclosed
CN-103200926-B Acrylate copolymer thickener 路博润高级材料公司 2016-11-09 CN disclosed
CN-103068856-B The blend of acrylic copolymer thickening agent 路博润高级材料公司 2016-08-03 CN disclosed
CN-105793273-A Dihydroxyalkyl-substituted polygalactomannans and methods of making and using same 赫尔克里士公司 2016-07-20 CN disclosed
CN-105705485-A Mesitylene sulfonate compositions and methods thereof 克劳罗克斯公司 2016-06-22 CN disclosed
CN-103068865-B Structured acrylate copolymer thickeners LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-01-13 CN disclosed
CN-103153277-B Polymer and compositions LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-11-25 CN disclosed
CN-102159593-B Cationic polymers and fixative applications therefor LUBRIZOL ADVANCED MAT INC 2014-07-09 CN disclosed
CN-103379889-A Structured acrylate copolymer for use in multi-phase systems LUBRIZOL ADVANCED MAT INC 2013-10-30 CN disclosed
CN-102648238-A Hydrolytically stable multi-purpose polymers LUBRIZOL ADVANCED MAT INC 2012-08-22 CN disclosed
US-20120191214-A1 Hydraulic Cement-Based Implant Material and Use Thereof INNOTERE GMBH (DE) 2012-07-26 US disclosed
CN-102202639-A Copolymers useful as rheology modifiers and home and personal care compositions BASF SE 2011-09-28 CN disclosed
CN-102159593-A Cationic polymers and fixative applications therefor LUBRIZOL ADVANCED MAT INC 2011-08-17 CN disclosed
CN-102088949-A Ester Compounds for Personal Care Products LUBRIZOL ADVANCED MAT INC 2011-06-08 CN disclosed
CN-101404978-A Polymers containing silicone copolyol macromers and personal care compositions containing same LUBRIZOL ADVANCED MAT INC (US) 2009-04-08 CN disclosed
CN-1320010-C Multi-purpose polymers, methods and compositions NOVEON IP HOLDINGS CORP (US) 2007-06-06 CN disclosed
CN-1929811-A Multi-purpose polymers, methods and compositions NOVEON INC (US) 2007-03-14 CN disclosed
CN-1703432-A Multi-purpose polymers, methods and compositions NOVEON IP HOLDINGS CORP (US) 2005-11-30 CN disclosed
US-3960564-A Physical development process utilizing a physical developer containing a specific reducing agent, a thiol compound U.S. PHILIPS CORPORATION (US) 1976-06-01 US disclosed